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Schmitt Emmanuelle
PERSONNEL DE RECHERCHE

Contact

Bureau : 84:30-18
Téléphone : +33169334885
Département/Laboratoire/Service : CA/DER/LAB/BIOC

Bibliographie & travail en cours

Biographie: 

Emmanuelle SCHMITT

 

11-01-1968 Buzancy (08)

 

POSITION AND EMPLOYMENT

  • 2010-present  Senior scientist at CNRS, Laboratory of Biochemistry, Palaiseau, France
  • 1998                 Permanent researcher position at CNRS, Laboratory of Biochemistry, Palaiseau, France
  • 1996-1997      Postdoctoral research fellow, Department of Structural Biology, IGBMC Strasbourg, Adviser Dr.  D. Moras
  • 1994-1996      Lecturer at Ecole Polytechnique, Department of Biochemistry, Palaiseau, France

 

TEACHING

  • 1998-present   Responsible for a master 2 integrated 2-week course. University of Paris-Saclay.
  • 1998-2012       Half-time Lecturer. Ecole Polytechnique, Department of Biology, Palaiseau, France

 

EDUCATION

  • 2006               Habilitation to conduct researches (HDR)
  • 1994               Ph.D. from Ecole Polytechnique,  Department  of  Biochemistry, Palaiseau,  France  
  • 1990               Engineer degree from « French Grande-Ecole, Institut National Agronomique de Paris-Grignon »

 

HONORS, MEMBERSHIPS AND AWARDS

  • 2011-present      Board member of the INRA Specialized Scientific Commission SIAMM (Science and Engineering of Food, Materials, Molecules for chemistry and Energy).
  • 2010-2016          Member of the Peer-Review committee 5 for biology and health at synchrotron SOLEIL.
  • 2010-present      Member of the management board of the SFBBM (French society for biochemistry and molecular biology). Vice-president from 2013.
  • 2013-present      Member of AFC (French association for crystallography).
  • 2003                     Bronze medal CNRS (life sciences).
Enseignement: 

BIO651:Relations structure-fonction des protéines et des acides nucléiques

Publications et Liens

Publications: 

Publications 2014-2018

  • Monestier A, Lazennec-Schurdevin C, Coureux PD, Mechulam Y, Schmitt E. Role of aIF1 in Pyrococcus abyssi translation initiation. Nucleic Acids Res. (2018) doi: 10.1093/nar/gky850.
  • Schmitt E, Bourgeois G, Gondry M, Aleksandrov A. Cyclization Reaction Catalyzed by Cyclodipeptide Synthases Relies on a Conserved Tyrosine Residue. Sci Rep. (2018) doi: 10.1038/s41598-018-25479-5.
  • Visweshwaran SP, Thomason PA, Guerois R, Vacher S, Denisov EV, Tashireva LA, Lomakina ME, Lazennec-Schurdevin, C, Lakisic G, Lilla S, Molinie N, Henriot V, Mechulam Y, Crews CM, Alexandrova AY, Perelmuter VM, Cherdyntseva NV, Bièche I, Schmitt  E, Insall  RH, Gautreau A. A trimeric coiled coil protein promotes WASH complex assembly. EMBO J. (2018).  doi: 10.15252/embj.201797706.
  • Bourgeois G, Seguin J, Babin M, Belin P, Moutiez M, Mechulam Y, Gondry M and Schmitt E. Structural basis for partition of the cyclodipeptide synthases into two subfamilies. J. Struct. Biol. (2018) 203:17-26. doi: 10.1016/j.jsb.2018.03.001.
  • Monestier A, Aleksandrov A, Coureux PD, Panvert M, Mechulam Y, Schmitt E. The structure of an E. coli tRNAfMet A1-U72 variant shows an unusual conformation of the A1-U72 base pair. RNA. (2017) doi: 10.1261/rna.057877.116.
  • Coureux PD, Lazennec-Schurdevin C, Monestier A, Larquet E, Cladière L, Klaholz BP, Schmitt E, Mechulam Y. (2016) Cryo-EM study of start codon selection during archaeal translation initiation. Nat Commun. 7:13366. doi: 10.1038/ncomms13366.
  • Panvert M, Dubiez E, Arnold L, Perez J, Mechulam Y, Seufert W, Schmitt E. (2015) Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. Structure. 23:1596-1608.
  • Chung WJ, Heddi B, Schmitt E, Lim KW, Mechulam Y, Phan AT. (2015) Structure of a left-handed DNA G-quadruplex. Proc Natl Acad Sci U S A.,112. 2729-2733
  • Dubiez E, Aleksandrov A, Lazennec-Schurdevin C, Mechulam Y, Schmitt E. Identification of a second GTP-bound magnesium ion in archaeal initiation factor 2. Nucleic Acids Res. (2015), 43. 2946-2957.
  • Moutiez M*, Schmitt E*, Seguin J, Thai R, Favry E, Belin P, Mechulam Y, Gondry M. Unravelling the mechanism of non-ribosomal peptide synthesis by cyclodipeptide synthases. Nat Commun., (2014) 5:5141. * : first co-authors.
Publications HAL: 
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Hal

Publications HAL: 

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